Available on the ixon Ultra 897 camera, the Optically Centred Crop Mode from Andor offers extremely fast frame rate performance from Region of Interest (ROI), and is ideally matched to the speed and sensitivity needs of live cell super-resolution microscopy. For example, a frame rate of 569 fps is achievable from a 128 x 128 ROI, a factor of 2 – 3x faster than competing EMCCD cameras with the same ROI. The mode will also be of interest for ion signalling, fluorescence correlation microscopy and astronomy adaptive optics. The ixon is available to ship with the OptoMask accessory.