Merck has developed and launched Seccosept, a septum closure for its Seccosolv dried solvent range. It incorporates a special cap that can be rotated over a precisely fitted septum (a teflon-coated silicone sealing disk). Five apertures in the rotating cap expose extra-large circular areas of septum each for repeated puncturing. This represents a benefit compared to smaller septum areas which are prone to irreversible damage when punctured repeatedly. The silicone used has outstanding self-sealing properties that allow rapid sealing of the puncture site. The rotating cap allows each of the five septum areas to be selected in turn, so that only the area that is currently being used is exposed. After removing the solvent the user turns the cap to the closed position now the fresh puncture site is immediately protected from potential contaminants.