CCR10 antibody
Product type
Primary antibodies
Description
Goat polyclonal to CCR10
Immunogen
Synthetic peptide: KPTEQVSWGLYSGYDEEAYSVGPLPELC, corresponding to amino acids 4-31 of Mouse CCR10.
Species Reactivity
Reacts with Mouse.
Not yet tested in other species.
BLAST 'KPTEQVSWGLYSGYDEEAYSVGPLPELC' with or
Specificity
Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region.
Relevance
Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 which displays chemotactic activity for resting CD4+ and CD8+ T cells.
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen.
The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 which displays chemotactic activity for resting CD4+ and CD8+ T cells.
Primary antibodies
Description
Goat polyclonal to CCR10
Immunogen
Synthetic peptide: KPTEQVSWGLYSGYDEEAYSVGPLPELC, corresponding to amino acids 4-31 of Mouse CCR10.
Species Reactivity
Reacts with Mouse.
Not yet tested in other species.
BLAST 'KPTEQVSWGLYSGYDEEAYSVGPLPELC' with or
Specificity
Peptide sequence is < 50 % identical to other mouse chemokine receptors in this region.
Relevance
Receptors for the CC chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The CC receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 which displays chemotactic activity for resting CD4+ and CD8+ T cells.
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen.
The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation.
CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 which displays chemotactic activity for resting CD4+ and CD8+ T cells.
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