Mithras LB 940 offers all comprehensive technologies used in today´s research:
- Absorbance
- Luminescence
- BRET
- AlphaScreen®
- Fluorescence
- FRET
- Fluorescence Polarisation (FP)
- Time-Resolved Fluorescence
- HTRF®
BERTHOLD TECHNOLOGIES has based its development on DOPS – Dedicated Optical Path System - to ensure the best available performance for each technology.
Mithras can be supplemented with up to 4 reagent injectors – based on the proven and highly precise and accurate JET injection technology – and a temperature control unit for the microplates.
All these features offer extensive opportunities to the users to perform a huge number of applications including kinase activities, second messengers (e.g. cAMP, IP-One), GPCRs, phagocytosis, calcium flux, cell viability, apoptosis, protein and DNA determinations, reporter gene assays or protein-protein interactions.
The software is supporting a multitude of functions including standard curves and kinetic data reduction as well as the 21 CFK part 11 requirements.
For medium level throughput environments such as ´assay development´ or ´secondary screening´ the instrument can be equipped with a stacker.
HTRF is a registered trademark of Cisbio. AlphaScreen is a registered trademark of PerkinElmer.
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