Harvesting Technology for High Cell Density Cultures

Sartorius Stedim Biotech has introduced Sartoclear Dynamics, a clarification system featuring new single-use technology for harvesting mammalian cell cultures with high cell densities.

Specially designed for cGMP processing, the system consists of prefilled single-use bags containing ultrapure diatomaceous earth (DE) in a choice of 0.5 kg to 10 kg. With a new quick-connect adapter for dust-free powder transfer, DE can be directly mixed into the cell culture fluid. This porous filter aid prevents blockage of the system’s filters. As the system maintains a constant ratio of biomass and filter aid, users can benefit from continuous maximum filter performance.