Enhancing Nano LC for Proteomics

Eksigent introduces its Chiplc-nanoflex System, delivering improved reproducibility and ease of use to proteomics research. The system is a docking station for up to three microfluidic chips that contain nano LC or trap columns. The companys proprietary Eksport microconnector system ensures reliable and consistent fluidic connections to facilitate column changes. Chips can be interchanged in seconds, even by inexperienced users, with minimal dead volume to compromise resolution. The proprietary microfabrication process used for both the trap chips and analytical column chips delivers exceptional column-to-column reproducibility. Superior-quality separations and reproducibility are critical to the success of nano LC-MS-based biomarker validation studies. In these applications, where peptides are measured by multiple reaction monitoring (MRM), the improved column-to-column reproducibility delivered by the system helps in obtaining consistent data from large numbers of samples.