GE Healthcare has introduced Mammalian Protein Extraction Buffer and Yeast Protein Extraction Buffer Kit, for efficient high quality extraction of soluble protein from mammalian cultured cells and yeast cell respectively. Both products are mild, non-denaturing buffer compositions, delivering high quality protein lysate compatible with most downstream applications without the need for mechanical cell lysis. Mammalian Protein Extraction Buffer is a 500 ml solution designed for extraction of total soluble proteins from mammalian cultured cells. The buffer can be used for both cell suspensions and adherent cells. The Yeast Protein Extraction Buffer Kit is designed for extraction of soluble proteins from yeast cells, and is suitable for preparation of approximately 10ml yeast cell pellet suspension, either as a single preparation or as multiple, smaller preps.