Agilent Technologies has introduced its 6410B triple quadrupole (QQQ) mass spectrometer (MS), and the company announced the sale of the 500th Agilent 6410 QQQ in less than two years since the platform was introduced. The new B version of the Agilent 6410 features polarity switching scans every 500 msec, allowing complex mixtures of compounds with strong fragmentation in positive and negative ion mode to be analysed in a single run. The Agilent 6410B doubles the number of Multiple Reaction Monitoring (MRM) scans that can be performed in a given time segment and also increases the maximum number of MRMs per method to more than 10,000. Users can create more efficient methods to analyse more compounds in a shorter timeframe.