New Aequorin Option for Screening System

Molecular Devices, a division of MDS Analytical Technologies and a leader in innovative solutions for drug discovery and life sciences, announced a new aequorin option for its FLIPR Tetra fluorometric imaging plate reader. This addition to the system includes the uniquely designed camera that can detect both fluorescence and aequorin luminescence and a new cell suspension option. Both the camera and cell suspension option were optimized on FLIPR Tetra to enable researchers to expand their calcium mobilization assays to include aequorin luminescence measurements. Unique to the system is a single camera to monitor aequorin luminescence and fluorescence-based calcium and membrane potential assays. Sensitivity can be adjusted to the appropriate assay signal window to detect dim aequorin cell lines while maintaining the ability to screen using traditional fluorescence methods.