bio-t® bag – the disposable Bioreactor System

The disposable bioreactor system from zeta allows you to step into the disposable age. The popular single-use cultivation system represents a successful collaboration between Meissner and zeta. The DPSTM bag technology from Meissner and zeta’s classical fermentor knowledge from bio-t® mini and bio-t® pro combined with the innovative agitation system makes the disposable bioreactor system from zeta a powerful tool for the upcoming future trend.

Bioreactor System:

• Presterilized, disposable bio-t® bag with integrated single-use measuring probes and mixing element allowing a gasket free agitation
• Open, double jacket stainless steel supporting container to take up disposable bag for heating and cooling
• Vibro mixer with frequency and amplitude for free configuration
• Bioreactor platform to hold vibro mixer and supporting container into position
• Bag hanger to take up all supply bags for acid, base and nutrient addition or sampling.
  

Control System:
Hardware:

• Compact and easy to clean stainless steel housing
• Control system with 8“ color touch screen
• Heating circuit
• Controller for temperature, agitation (frequency and amplitude), pH and pO2
• 4 free to configure peristaltic pumps and rotameter
• Connections for external pumps, pressure sensor and balance
• Gas mixing station
  

Software Evolution® mini:

• Simple menu-driven data entry
• Measurement of various process parameters
• Trend visualization and alarming
• Manual or automatic control mode
• Calibration menu
• Password protected access levels
• Time depended set point profile (Ramp function)
• Cascade control for aeration (gas mix/agitation/feed)
  

SCADA:

• Visualization and trending of process data on external PC
• Data export to Excel
  

Predefined packages of the bio-t® bag disposable bioreactor system are available for bacterial culture and cell culture. In addition the gas mixing station can be realized in three different versions: Standard, Pulse Flow Control and Continuous Flow Control. The complete disposable bioreactor line is available in for up-scale within 3L, 15L, 75L, 375L and 1875L total volume.

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