BD PuraMatrix Peptide Hydrogel is a synthetic matrix that is used to create defined three-dimensional microenvironments for a variety of cell culture experiments. To achieve optimal cell growth and differentiation, it is necessary to determine the appropriate mixture of this material and bioactive molecules (e.g., growth factors, extracellular matrix proteins, and/or other molecules). BD PuraMatrix Peptide Hydrogel consists of standard amino acids (1% w/v) and 99% water. The hydrogel is readily formed in a culture dish, plate, or cell culture insert. The resulting hydrogel has been shown to promote the differentiation of hepatocyte progenitor cells1, rat pheochromocytoma cells (PC12)2, and hippocampal neurons.
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