Camag TLC-MS Interface: Plug & Play Extraction into MS

Hyphenating TLC/HPTLC with mass spectrometry opens new possibilities for reliable identification of chromatographic fractions. In the past unknown substances needed to be scraped off from the TLC/HPTLC plate, eluted into a tube and transferred offline into the MS.

With the TLC-MS Interface a very convenient and universal solution is available which is capable of semi-automatic extraction and online transfer into a connected HPLC-MS system. The instrument can be installed plug & play into any given MS system enabling rapid and contamination-free elution of selected zones.

Depending on the MS system questioned substances are directly extracted from the TLC/HPTLC plate and identified within less than a minute via its mass spectrum, or for unknown substance zones the respective sum formula can be obtained. The limit of detection is similar to HPLC-MS.