The LSM 7 MP Laser Scanning Microscope from Carl Zeiss is tailored to the needs of multiphoton microscopy, offering flexibility, a compact design and ease of use. It generates high resolution microscopic images for a broad range of experiments in biomedical and basic research. Thanks to the use of two scanners in one compact system, two lasers with different wavelengths can be utilized sequentially or simultaneously for specimen imaging and manipulation. The range of detectors and their filter equipment, as well as an extensive line of microscope accessories, allow customization of the microscope system. Applications include e.g. high resolution 3D imaging in long-term process observations, and functional imaging in conjunction with simultaneous photo-manipulation.