Application Poster

Guava Technologies application poster Detection of compounds inducing distinct caspase pathways describes how researchers, using a Guava Easycyte Plus System and the Guava Caspase Software Module, tested a series of 165 cytotoxic, immunosuppressive, anti-proliferative, and anti-inflammatory compounds for their ability to induce apoptosis using non-adherent human T cells (Jurkat) and adherent human cervical cancer cells (Hela). The application poster demonstrates how using a combination of proprietary assays enables the elucidation of whether one or the other, or both pathways, is primarily induced and what the potency of the various compounds is for inducing a particular pathway.