New Real-Time Microarray Platform

HybLive, the recently developed open real-time microarray platform from Genewave integrates hybridisation, washing, and detection functionalities within a single benchtop instrument, thus facilitating full microarray-based assay automation. In addition, and in contrast to standard tools, HybLive system makes it possible to monitor target molecule hybridisation and melting in real time, directly on the chip. This innovation opens the way to many applications that were inaccessible until now, such as on-chip probe verification and validation or the definition of optimal hybridisation conditions over a single experiment, melting curve measurement or the study of on-chip intermolecular interactions, SNP detection, etc. The system is compatible with standard format microarray slides and offers the possibility of using up to four detection channels (colours). HybLive platform is the ideal tool for DNA or protein microarray assay development, and may also be routinely used in basic and clinical research.