Fluorescence In Situ Hybridization, or FISH, is an exciting fluorescence imaging technique that enables clinical-scale genetic screening based on molecular diagnostics. AHF analysentechnik AG offers hard-coated BrightLine® filters that are significantly brighter than and have superior contrast to older, soft-coated fluorescence filters, thus offering faster and more accurate measurements. Independent evaluations have shown that FISH images can be obtained in as little as one half the exposure time using BrightLine® filters. And because BrightLine® filters are virtually impervious to humidity and temperature-induced shifting, can be readily cleaned and handled, and will not “burn out” under normal conditions, even with prolonged use and intense UV irradiation, they perform identically year after year, thus further lowering the cost of ownership.