Thermo Fisher Scientific has introduced a Liquid Handling Module for the Arrayscan VTI HCS Reader. Synchronous dispense-while-imaging capability, combined with kinetic image capture, a range of image analysis algorithms, and on the fly processing, allow the real-time capture of cellular phenotypes and rapid biological responses. Furthermore, multiple aspirate/dispense options enable dye loading, media replacement, incubation and stimulus addition to be fully automated. The system provides an automated solution for pharmacological studies, including GPCR biology, cell pathway analysis, compound pharmacology and In Vitro toxicology.