Scanner Technology for TIRF

The Wetzlar, Germany-based optics manufacturer has developed a scanner technology for Total Internal Reflection Fluorescence (TIRF) that greatly simplifies this otherwise very complicated technique. With the Leica AM TIRF, users can concentrate completely on their research work, while leaving instrument operation up to a powerful software program. Vesicle transport examinations, analysis of interactions between molecules, applications in membrane research and even single molecule examinations can be tailored to specific needs using the Leica AM TIRF. The software-controlled TIRF scanner automatically finds the correlation between the penetration depth of the evanescent field and the corresponding TIRF angles. With the Leica AM TIRF, complicated manual settings and complex calculations are unnecessary - the intelligent Leica AF6000 fluorescence software assumes these tasks, making the system convenient and easy to use.