Innovative Technology for LPS Removal
Profos a successful and steadily growing German biotech company uses the highly specific interaction of naturally occurring bacteriophages with their bacterial host to develop effective tools for the detection and isolation of bacteria. Endotoxins (LPS) which are found in Gram-negative bacteria frequently cause contamination problems when dealing with biological solutions.
LPS exhibits strong biological effects in cell culture and shows severe toxicity to humans and animals when entering the blood stream. Profos has developed an innovative system for the effective removal of LPS EndoTrap which combines the ability to quickly and efficiently eliminate LPS from solutions, along with excellent target recovery rates. It is an affinity chromatography system based on extremely specific protein ligands which bind to a conserved region of LPS of most Gram-negative bacterial strains.
EndoTrap can be regenerated and reused for several removal rounds without loss of LPS binding efficiency. The protocol of EndoTrap is user friendly, does not need training or special equipment and yields rapid results as it is designed as a flow-through system. The EndoTrap technology is currently the most powerful and convenient solution for LPS contamination problems and can be scaled up for lab research and industrial applications.In order to assist customers dealing with difficult product/buffer combinations or to ensure optimal endotoxin removal for routine use, Profos is pleased to be able to offer also an optimisation and removal service with EndoTrap. Profos also offers an endotoxin detection service using a quantitative, kinetic chromogenic LAL assay.
LPS exhibits strong biological effects in cell culture and shows severe toxicity to humans and animals when entering the blood stream. Profos has developed an innovative system for the effective removal of LPS EndoTrap which combines the ability to quickly and efficiently eliminate LPS from solutions, along with excellent target recovery rates. It is an affinity chromatography system based on extremely specific protein ligands which bind to a conserved region of LPS of most Gram-negative bacterial strains.
EndoTrap can be regenerated and reused for several removal rounds without loss of LPS binding efficiency. The protocol of EndoTrap is user friendly, does not need training or special equipment and yields rapid results as it is designed as a flow-through system. The EndoTrap technology is currently the most powerful and convenient solution for LPS contamination problems and can be scaled up for lab research and industrial applications.In order to assist customers dealing with difficult product/buffer combinations or to ensure optimal endotoxin removal for routine use, Profos is pleased to be able to offer also an optimisation and removal service with EndoTrap. Profos also offers an endotoxin detection service using a quantitative, kinetic chromogenic LAL assay.
This product information
is expired!
Use our search-function for current products ...
is expired!
Use our search-function for current products ...
